Systematic expression analysis of ligand-receptor pairs reveals important cell-to-cell interactions inside glioma
Abstract Background Glioma is the most commonly diagnosed malignant and aggressive brain cancer in adults.Traditional researches mainly explored the expression profile of glioma at SEA KELP cell-population level, but ignored the heterogeneity and interactions of among glioma cells.Methods Here, we firstly analyzed the single-cell RNA-seq (scRNA-seq